Robert-Rössle-Str. 10
13125 Berlin
Germany
Phone: +4930-9489-2330
Fax: +4930-9489-2341
Description:
PSF biotech (“the protein structure factory®”) merges Structural Proteomics with Structure-Based Drug Desgin (SBBD)
Services:
PSF offers comprehensive services all along the way from a DNA clone to the structural characterization of a specific protein alone or complexed with ligands. Expression and purification of recombinant proteins, crystallographic structural analysis by high-throughput protein crystallography as well as NMR techniques have been successfully provided to many biotechnology and pharmaceutical companies.
Technology:
The company’s technology platform consists of bioinformatics modules, protein production units with various host systems available, biophysical characterization units, NMR spectroscopy and synchrotron-based protein crystallography.
Based on the 3D-structure of a protein target, small molecules that bind specifically can be identified and subsequently modified to yield high quality lead candidates for new drugs.