PSF biotech (“the protein structure factory®”) merges Structural Proteomics with Structure-Based Drug Desgin (SBBD)
PSF offers comprehensive services all along the way from a DNA clone to the structural characterization of a specific protein alone or complexed with ligands. Expression and purification of recombinant proteins, crystallographic structural analysis by high-throughput protein crystallography as well as NMR techniques have been successfully provided to many biotechnology and pharmaceutical companies.
The company’s technology platform consists of bioinformatics modules, protein production units with various host systems available, biophysical characterization units, NMR spectroscopy and synchrotron-based protein crystallography.
Based on the 3D-structure of a protein target, small molecules that bind specifically can be identified and subsequently modified to yield high quality lead candidates for new drugs.