SinoBio Biotech

Cailun RD #720
Shanghai 201203
China

Phone: 08621-5079-8028
Stock symbol: SNBB

Description:

SinoBio Biotech’s purification development group has developed purification processes for a wide variety of recombinant proteins. Many of these process development projects are undertaken in collaboration with the customer’s process development and analytical scientists. A wide range of chromatographic operations have been used for the purification of recombinant proteins (e.g. ion exchange, hydrophobic interaction, affinity, ceramic Hydroxyapatite, metal chelate, gel permeation, etc.).

Scientists in SinoBio Biotech have taken part in 9 protein drugs process development. That is one third of biologics in China protein drug market. In the past three years SinoBio Biotech have established about 400 different proteins manufacture process scale from milligram to tens of gram. About 40 cytokines and tens of enzymes are qualified by well known reagent and cytokine sellers and contract all over the world. Five of them are get into preclinical trials and one of them filed IND.

PROCESS DEVELOPMENT

Points to consider in developing a biopharmaceutical process include: protein purity, scale-up requirements, yield, practical manufacturability and overall cost.